The trial involved around 30,000 people in total. What benefits of Spikevax have been shown in studies?Ī very large clinical trial showed that Spikevax, given as a two-dose regimen, was effective at preventing COVID 19 in people from 18 years of age. If, later on, the person comes into contact with SARS-CoV-2, their immune system will recognise it and be ready to defend the body against it.Īfter vaccination the mRNA from the vaccine is broken down and removed from the body. The person’s immune system will then recognise this protein as foreign and produce antibodies and activate T cells (white blood cells) to attack it. When a person is given the vaccine, some of their cells will read the mRNA instructions and temporarily produce the spike protein. An adapted vaccine works in the same way as the original vaccine and is expected to broaden protection against the virus as it also contains mRNA matching other variants of the virus. This is a protein on the surface of the SARS-CoV-2 virus which the virus needs to enter the body’s cells and can differ between variants of the virus. It contains a molecule called mRNA which has instructions for making the spike protein. Spikevax works by preparing the body to defend itself against COVID-19. The vaccines should be used according to official recommendations, issued at national level, by public health bodies.įor more information about using Spikevax and its adapted vaccines, see the package leaflet or consult a healthcare professional. Adults and adolescents from the age of 12 years are given 50 micrograms per dose and children aged 6 to 11 years are given 25 micrograms per dose. Adults and adolescents from the age of 12 years are given 50 micrograms per dose and children aged 6 to 11 years are given 25 micrograms per dose.Ī booster dose of Spikevax bivalent Original/Omicron BA.4-5 may be given to adults and children from the age of 6 years, at least 3 months after primary vaccination or a booster dose with a COVID-19 vaccine. Adults and adolescents from the age of 12 years are given 50 micrograms per dose and children aged 6 to 11 years are given 25 micrograms per dose.Ī booster dose of Spikevax bivalent Original/Omicron BA.1 may be given to adults and children from the age of 6 years, at least 3 months after primary vaccination or a booster dose with a COVID-19 vaccine. Adults and adolescents from the age of 12 are given 100 micrograms per dose, children aged 6 to 11 years are given 50 micrograms per dose, and children aged 6 months to 5 years are given 25 micrograms per dose.Īn additional dose of Spikevax may be given to people aged 6 years and older with a severely weakened immune system, at least 28 days after their second dose.Ī booster dose of Spikevax may be given to adults and children from the age of 6 years, at least 3 months after primary vaccination with Spikevax, or another mRNA vaccine or an adenoviral vector vaccine. Spikevax is given as two injections, usually into the muscle of the upper arm, or the thigh in infants and young children, 28 days apart.
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